Direkte orale Antikoagulantien in der Notfallmedizin

Forschungsschwerpunkte

Durch den Aufbau des Berner NOAC-Register (BerNOAC) mit Einschluss aller Notfallpatienten unter den neuen oralen oralen Antikoagulantien arbeitet die Arbeitsgruppe daran, Blutungskomplikationen unter neuen direkten oralen Antikoagulantien besser zu verstehen und ihr Behandlung zu verbessern.

Aktuelle Projekte

  • Blutungskomplikationen in speziellen Patientengruppen (geriatrische Patienten, Patienten mit Niereninsuffienz)
  • Medikamentenspiegelmessungen

Mitarbeitende und ständige Kooperationen

  • Prof. Dr. med. Aristomenis Exadaktylos
  • PD Dr. med. et. phil. Michael Nagler, Universitätsinstitut für Klinische Chemie (UKC)
  • Jolanta Klukowska-Rötzler
  • PD Dr. med. vet. Meret Ricklin
  • PD Dr. med. Martin Müller
  • Study-Nurses, Masterstudenten und Dissertanten

Publikationen

Müller M, Bosshard F, Nagler M, Roth B, Exadaktylos AK, Sauter TC. Shorter Hospital Stay and Fewer Hospitalizations in Patients With Visible Hematuria on Direct Oral Anticoagulants Compared to on Vitamin K Antagonists. Urology. 2019 Oct;132:101-108

Müller M, Schlittler F, Schaller B, Nagler M, Exadaktylos AK, Sauter TC. Characteristics, treatment and outcome of bleeding after tooth extraction in patients on DOAC and phenprocoumon compared to non-anticoagulated patients-a retrospective study of emergency department consultations. Clin Oral Investig. 2019 May;23(5):2273-2278

Müller M, Eastline J, Nagler M, Exadaktylos AK, Sauter TC. Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists. Scand J Trauma Resusc Emerg Med. 2019 Apr 23;27(1):48.

Sauter TC, Eberle B, Wuillemin WA, Thiele T, Angelillo-Scherrer A, Exadaktylos AK, Erdoes G, Cuker A, Nagler M. How I manage patients with anticoagulation-associated bleeding or urgent surgery. Swiss Med Wkly. 2018 Mar 14;148:w14598.

Sauter TC, Hegazy K, Hautz WE, Krummrey G, Ricklin ME, Nagler M, Borner U, Exadaktylos AK. Epistaxis in anticoagulated patients: Fewer Hospital admissions and shorter Hospital stays on rivaroxaban compared to phenprocoumon. Clin. Otolaryngol. 2017 May 16.

Sauter TC, Amylidi AL, Ricklin ME, Lehmann B, Exadaktylos AK. Direct new oral anticoagulants in the emergency department: Experience in everyday clinical practice at a Swiss university hospital. Eur J Intern Med. 2016 Apr;29:e13-5.

Sauter TC, Blum S, Nagler M, Schlittler FL, Ricklin ME, Exadaktylos AK. Reversal of Dabigatran Using Idarucizumab in a Septic Patient with Impaired Kidney Function in Real-Life Practice. Case Rep Emerg Med. 2016;2016:1393057.

Sauter TC, Melis C, Hautz WE, Ricklin ME and Exadaktylos AK, Direct new oral anticoagulants: follow-up, guidelines and bleeding complications in general practice—a survey of Swiss general internal medicine practitioners. SpringerPlus 2016 5:2030, 2016